Which supplement helps you keep up your energy and focus through a long workday?

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Energy and focus

Which supplement helps you keep up your energy and focus through a long workday?

It depends on what is going wrong. For a healthy adult, a moderate amount of caffeine is what most directly helps you stay alert, but it does not replace sleep and can harm it; if the tiredness lasts for weeks, what you need to do is look for the cause.

9 min read · Published 23 Oct 2026
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Before you choose a product, it helps to know whether you need to stay alert for a few hours, whether you suspect a deficiency or whether you are carrying tiredness that will not go away. Each case has a different answer, and in two of them the answer does not start with a supplement.

01What is going wrong

The best choice depends on what is going wrong

Needing to be alert first thing is not the same as dragging tiredness around every day. This table sums up what makes sense to check in each case and where the limit of each option lies.

What to check depending on what is happening to you
If this happens to you What makes sense to check The limit
You occasionally struggle to stay awake A source of caffeine with a known amount It can cause jitteriness and affect sleep
You lack focus after too little sleep Sleep, food, water and breaks before adding another product A stimulant can mask the problem for a few hours
You think you are low in iron or a vitamin Confirm it with a blood test and, if appropriate, take a prescribed supplement Taking them when you do not need them is not an energy strategy
You have been tired for weeks Look for the cause with a healthcare professional A supplement does not replace an assessment
When it is not about supplements

Caffeine helps you stay alert, but it does not resolve the cause of tiredness, which may lie in sleep, stress, diet, medication or an illness. The NHS recommends seeing a GP if you have been tired for a few weeks without knowing why, if the tiredness affects your daily life or if it comes with other symptoms.

02Caffeine

Caffeine is the most direct option, but the amount matters

For healthy adults, EFSA concludes that single doses of up to 200 mg, and up to 400 mg a day spread across the day and counting all sources, do not raise safety concerns. The daily figure does not cover pregnant women, whose reference is up to 200 mg a day, and EFSA itself warns that 100 mg close to bedtime can affect sleep in some people.

  • 100mgClose to bedtime, can affect sleep in some people
  • 200mgReference single dose for healthy adults
  • 400mgPer day for healthy adults, counting all sources

EFSA reference values for healthy people, not a daily target or an individual recommendation.

Your daily total includes coffee, tea, cola, energy drinks, chocolate, some medicines and other supplements, and the caffeine in a cup varies a lot depending on the type of coffee and how it is made. The NIH Office of Dietary Supplements notes that caffeine can reduce the feeling of fatigue and that, from 500 mg a day, it can disrupt sleep and cause irritability or anxiety.

In practice

If caffeine gives you anxiety, palpitations, digestive discomfort or insomnia, cutting the amount or taking it earlier may make more sense than looking for a stronger formula.

03How to compare

A formula with many ingredients does not prove it works better

Before you buy a supplement for energy and focus, check five things:

  1. Amount per dose. "Ginseng", "bacopa" or "vitamin B" is not enough: the label has to say how much of each ingredient it provides.
  2. Total caffeine. Add the product's caffeine to what you get from your drinks and other supplements.
  3. Time of day. What keeps you alert in the morning can harm your rest if you take it late.
  4. Warnings. Pregnancy, breastfeeding, age, caffeine sensitivity, medication and diagnosed medical conditions.
  5. Evidence for the whole formula. A study on one ingredient does not show that a commercial combination produces the same result.

On performance supplements, the NIH warns that many combine ingredients that have not been tested together, that ingredients can act differently when combined and that, because most of those combinations have not been studied, it is not known how effective or how safe they are. A long list of actives is transparent if it declares the amounts, but on its own it does not prove that the product is better than a simple option.

What is more, a supplement is not a medicine: AESAN defines supplements as concentrated sources of nutrients or other substances with a nutritional or physiological effect, which must be taken at the dose on the label, do not replace a balanced diet and are not meant to prevent or treat diseases.

In practice

The step-by-step guide to reading a label, with a real example, is in our guide How to choose a capsule supplement to help you focus.

04Comparison

Coffee, a multi-ingredient formula or caffeine-free

There is no single best option for everyone: it depends on what is going wrong.

When each option fits and what its limit is
Option Fits if The limit
Coffee You already sleep well, tolerate caffeine and want an occasional boost you can adjust The caffeine in a cup varies a lot depending on the coffee and how it is made
Multi-ingredient formula You prefer a measured dose and several actives in a single morning serving Convenience does not prove it works better; check the amounts and caffeine
Caffeine-free formula Caffeine makes you jittery or you already have enough during the day If you are short of sleep or stressed, removing or adding stimulants does not resolve the cause
Persistent tiredness You have been tired for weeks or it affects your daily life No supplement replaces a medical assessment

If you see yourself in the second row, you can see the Energy + Focus formula and dose or keep reading: further down we explain where it fits and what it doesn't tell you.

05Routine

How to organise a long workday

  1. Be clear about the goal. Needing to be alert first thing is not the same as dragging tiredness around every day.
  2. Change only one thing at a time. The dose or the product, but not several stimulants at once.
  3. Take caffeine early. It can affect your sleep even when you no longer notice its effect.
  4. Count the daily total. Including tea, soft drinks, energy drinks, chocolate and medicines.
  5. Look after the basics. Sleeping, eating enough, drinking water and taking breaks to move are still part of the solution.
  6. Watch how you respond. If you get jitteriness, palpitations, digestive discomfort or insomnia, reduce the amount and ask for advice if it keeps happening.
06Where VENZE fits

Where Energy + Focus fits

Energy + Focus is our product, so take this for what it is: an option for people who prefer a measured dose of caffeine and several actives in a single morning serving, not the answer for everyone.

  • 2capsules early in the day, with breakfast
  • ≈75 mgof caffeine per daily dose, a little less than a coffee
  • 9actives with the amount declared on the label

The caffeine is microencapsulated (Newcaff®75). In its manufacturer's tests (Lipofoods), after 30 minutes it had released 24% versus 100% for regular caffeine: the energy arrives more gradually. The daily dose also provides 100% of the reference value for vitamin B12, which contributes to the reduction of tiredness and fatigue.

What each dose contains

  • L-tyrosine powder on a blue-grey background300 mgL-tyrosinePrecursor of dopamine
  • Crystals representing Cognizin® (citicoline)250 mgCognizin® (citicoline)Studied for brain energy metabolism
  • A sprig of Bacopa monnieri200 mgBacopa extract, with 80 mg bacosidesStudied for memory and information processing
  • A slice of rhodiola root200 mgRhodiolife® (rhodiola), with 6 mg rosavins and 3 mg salidrosidesStudied for mental fatigue
  • Ginseng root150 mgGinseng extract, with 15 mg ginsenosidesStudied for mental and physical energy
  • Three Newcaff®75 caffeine microcapsules100 mgNewcaff®75, with about 75 mg caffeineMicroencapsulated caffeine
  • Coenzyme Q10 powder50 mgCoenzyme Q10Involved in cellular energy production
  • Black peppercorns, the source of BioPerine®5 mgBioPerine®, with 4.75 mg piperineStudied for the absorption of other ingredients
  • Vitamin B12 powder2.5 µgVitamin B12, 100% of the NRVContributes to the reduction of tiredness and fatigue

The product page recommends taking it in the morning and not in the afternoon, because of the caffeine. You can combine it with coffee or tea, but it is worth adding up your total caffeine for the day and bearing in mind how well you tolerate it. If you only need an occasional boost and coffee agrees with you, a cup may be enough.

What it doesn't tell you

The studies cited are on the ingredients, not on the whole formula, so they allow us to talk about "contains" and "has been studied for", not about the same result in everyone.

See the Energy + Focus formula and dose
07Before you decide

Three questions before you choose

  1. Have you been tired for weeks without knowing why, or does the tiredness affect your daily life?
  2. Do you get enough sleep most nights?
  3. Do you know how much caffeine you have a day, counting all sources?

If yes to the first: check with a healthcare professional before trying a supplement.

If no to the second: sleep comes first; no stimulant makes up for it.

If no to the third: do the sum before adding another source of caffeine.

08Questions

Frequently asked questions

Is a supplement better than coffee for working long hours?

It depends on what you are looking for. Coffee lets you adjust the amount and the timing; a supplement with caffeine and other actives gives you a measured dose in a single serving. Compare the caffeine per dose, the declared amounts, the price per day and the warnings.

Can I take Energy + Focus with coffee?

The product page states that it can be combined with coffee and tea. Even so, add up all your sources of caffeine for the day, stick to the two-capsule dose and notice how it affects your sleep and how jittery you feel.

Is a caffeine-free formula better for focus?

It can be an option if caffeine makes you jittery or if you already have enough during the day. If your lack of focus comes with lack of sleep, stress or persistent tiredness, removing or adding stimulants does not necessarily resolve the cause.

When should I see a healthcare professional?

Before taking a supplement if you are pregnant or breastfeeding, take medication, have a diagnosed medical condition or are very sensitive to caffeine. And also if you have been tired for weeks without knowing why, if the tiredness affects your daily life or if it comes with other symptoms, as the NHS recommends.

How much caffeine is right for me?

There is no single figure. EFSA gives reference values for healthy adults, but pregnancy, breastfeeding, age, medication, illness and each person's sensitivity change the picture. Use the lowest amount that meets your goal and ask for advice if in doubt.